Computational methods in bioinformatics (2013-2014)

Lectures

DateTopic
Tuesday 29 October Introduction
Thursday 31 October Pairwise sequence alignment
Tuesday 5 November Protein conformation
Thursday 7 November Protein domains
Tuesday 12 November Macromolecular structure determination by X-ray crystallography
Thursday 14 November Macromolecular structure determination by NMR spectroscopy
Tuesday 19 November Structural alignment (introduction to individual topic);
Comparative modelling;
Side chain modelling (introduction to individual topic)
Thursday 21 November Discussion on main chain tracing;
Molecular mechanics;
Monte Carlo algorithms
Tuesday 26 November Lattice models (introduction to individual topic);
fold recognition (introduction to individual topic);
surface representation
channels (introduction to individual topic);
Thursday 28 November Docking;
Multi-resolution modelling (introduction to individual topic)
Tuesday 3 December De novo protein modelling
Thursday 5 December Protein design
Tuesday 10 December Presentations on individual topics
Thursday 12 December Presentations on individual topics
Last Modified: 4 December 2013 by Graham Kemp