Computational methods in bioinformatics (2017-2018)

Lecture 7

Fold recognition; De novo protein modelling; Lattice models

Aims

Objectives

After this lecture you will be able to:

Supplementary Material

Some of the lecture slides are available on-line (1 per page, 4 per page).

A detailed description of the derivation of pairwise potentials is given in: Sippl, M.J. (1990) Calculation of conformational ensembles from potentials of mean force: An approach to the knowledge-based prediction of local structures in globular proteins", 213, 859-883 (doi:10.1016/S0022-2836(05)80269-4)

The ab initio protein structure prediction algorithm introduced in this lecture is described in:

The zipping and assembly method is described in:


Last Modified: 19 November 2017 by Graham Kemp