Bioinformatics (2012/2013)
Essay on Next Generation Sequencing and Metagenomics
Task description
References
We recommend that you start your reading with the following papers:
-
Loman, N.J.,
Constantinidou, C.,
Chan, J.Z.M.,
Halachev, M.,
Sergeant, M.
Penn, C.W.,
Robinson, E.R. and
Pallen, M.J. (2012)
"High-throughput bacterial genome sequencing: an embarrassment of choice, a
a world of opportunity",
Nature Reviews Microbiology, 10, 599-606
doi:10.1038/nrmicro2850
-
Hugenholtz, P. and Tyson, G.W. (2008)
"Microbiology: Metagenomics",
Nature, 455, 481-483
doi:10.1038/455481a
-
Horner, D.S.,
Pavesi G.,
Castrignano, T.,
De Meo, P.D.,
Liunii, S.,
Sammeth, M.,
Picardi, E. and
Pesole, G (2010)
"Bioinformatics approaches for genomics and post genomics applications of
next-generation sequencing",
Brief. Bioinform., 11, 181-197
doi:10.1093/bib/bbp046
-
Metzker, M.L. (2010)
"Sequencing technologies - the next generation",
Nature Reviews Genetics, 11, 31-46
doi:10.1038/nrg2626
-
Mardis, E.R. (2008)
"The impact of next-generation sequencing technology on genetics",
Trends in Genetics, 24, 133-141
doi:10.1016/j.tig.2007.12.007
-
Pop, M. and Salzberg, S.L. (2008)
"Bioinformatics challenges of new sequencing technology",
Trends in Genetics, 24, 142-149.
doi:10.1016/j.tig.2007.12.006
All of these papers can be accessed from within the "chalmers.se" domain.
Cheating/Plagiarism
You should be aware of these guidelines:
Academic
Honesty and Integity at Chalmers.
Hand-in and deadline
Send your essay as a PDF file to marbuo@chalmers.se and kemp@chalmers.se before
17:00 on Friday 1 March 2013.
Ensure that your name is included in the document.
The essays will be available on the 8th outside Mariana's office (L3098,
Mathematical Sciences) on Friday 8 March 2013.
Last Modified: 15 February 2013
by Graham Kemp